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Design and Development of PSO-Firefly Hybrid Optimizer–CNN Model for Lung Disease Classification using Chest X-Ray Images

Tanu Dhiman1,*, Puneet Kumar1
1Department of Computer Science & Engineering, Chandigarh University, India
*Author to whom correspondence should be addressed:
E-mail: tanudhiman0707@gmail.com (TD)
Received: May 02, 2025 | Revised: October 14, 2025 | Accepted: March 16, 2026 | Published: March 2026
Abstract
Lung diseases such as Pneumonia, COVID-19, and Tuberculosis (TB) are major contributors to global mortality, making early and accurate diagnosis crucial for effective treatment. This paper introduces a novel Hybrid Nature-Inspired Optimizer – Convolutional Neural Network (HNI-CNN) model for the classification of lung diseases from chest X-ray images. The model integrates Particle Swarm Optimization (PSO) and Firefly Algorithm (FFA) to form a hybrid feature selection method, which optimizes the extraction of relevant features, significantly enhancing the classification accuracy. Additionally, Principal Component Analysis (PCA) is employed to reduce dimensionality, ensuring the model focuses on the most informative features. Tested on the Kaggle lung disease dataset, the HNI-CNN model achieves state-of-the-art performance, with an accuracy of 98.0%, precision of 96.8%, and recall of 99.0%, outperforming leading models such as NasNetMobile, MobileNetV2, and EfficientNetB1. This research presents a significant advancement in intelligent diagnostic systems by offering a more reliable and efficient method for feature selection and classification. The hybrid optimization approach not only improves performance but also enhances the robustness of automated medical diagnostics, making it a valuable tool for expert systems in healthcare.
Keywords
Deep Learning; Hybrid Optimizer with nature-inspired component –convolutional neural network (HNI-CNN); Lung X-ray Images; Medical Imaging
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  1. 1) Challenges and Issues
  2. 2) Handling Huge Image Size
  3. 3) Limited Available Datasets
  4. 4) High Correlation of Errors
  5. 5) Hybrid Feature Selection
  6. 6) Detection of Lung Chest X-Ray Images
  7. 7) Results and Performance Analysis
  8. 8) Mathematical Performance Evaluation
  9. 9) Mean Square Error Rate
  10. 10) Implementation Details
  11. 11) Visualization and Failure Analysis
  12. 12) Effectiveness of the Hybrid Optimization Strategy
  13. 13) Impact of PCA on Computational Efficiency
  14. 14) Improved Classification Performance
  15. 15) Interpretability Through Grad-CAM Visualizations
  16. 16) Analysis of Misclassifications
  17. 17) Clinical Applicability and Practical Value
  18. 18) Conclusion and Future Scope
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